Blar i forfatter "Ozolina, Agnese"

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    • Activation of Coagulation and Fibrinolysis in Acute Respiratory Distress Syndrome: A Prospective Pilot Study 

      Ozolina, Agnese; Sarkele, Marina; Sabelnikovs, Olegs; Skesters, Andrejs; Jaunalksne, Inta; Serova, Jelena; Ievins, Talins; Bjertnæs, Lars J.; Vanags, Indulis (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11-28)
      Introduction: Coagulation and fibrinolysis remain sparsely addressed with regards to acute respiratory distress syndrome (ARDS). We hypothesized that ARDS development might be associated with changes in plasma coagulation and fibrinolysis. Our aim was to investigate the relationships between ARDS diagnosis and plasma concentrations of tissue factor (TF), tissue plasminogen activator (t-PA), and ...

    • Polymorphisms on PAI-1 and ACE genes in association with fibrinolytic bleeding after on-pump cardiac surgery 

      Ozolina, Agnese; Strike, Eva; Nikitina-Zake, Liene; Jaunalksne, Inta; Krumina, Angelika; Lacis, Romans; Bjertnæs, Lars J.; Vanags, Indulis (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-09-04)
      Background: Carriers of plasminogen activator inhibitor -1 (PAI-1) -675 genotype 5G/5G may be associated with lower preoperative PAI-1 plasma levels and higher blood loss after heart surgery using cardiopulmonary bypass (CPB). We speculate if polymorphisms of PAI-1 -844 A/G and angiotensin converting enzyme (ACE) intron 16 I/D also might promote fibrinolysis and increase postoperative bleeding. ...

    • Thromboelastometry for Assessing Risks of Free Flap Thrombosis in Patients Undergoing Microvascular Surgery 

      Vanags, Indulis; Stepanovs, Jevgenijs; Ozolina, Agnese; Mukans, Maksims; Bjertnaes, Lars J.; Mamaja, Biruta (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-23)
      <p>Introduction</i>: Coagulation assessment is often missing in microvascular surgery. We aimed at evaluating the predictive value of thromboelastometry for free flap thrombosis in microvascular surgery patients.<p> <p> <i>Materials and Methods</i>: We enrolled 103 adult patients with traumatic injuries scheduled for microvascular free flap surgery into a prospective observational study. Thirty-six ...